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Trying to keep pace with demand Lilly acknowledged in its 2024 annual report, released in February 2025, that there were periods of time last year when demand for the companys incretin medicines exceeded production and while the supply of tirzepatide the active ingredient in Mounjaro and Zepbound currently exceeds demand in the U.S., its a situation that remains fluid

doi: 10.1111/dom.12829

This behavior is the core of Binge Eating Disorder (BED), which shares fundamental features with substance use disorders, such as: (1) a loss of control over intake, (2) persistence in the behavior despite adverse health consequences, and (3) the possible emergence of withdrawal symptoms when the food is restricted [29,30] and see Gearhardt et al., 2011 for a conceptual synthesis of BED and food addiction as overlapping but non-identical constructs [29]